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America’s Sweetheart Jennifer Anniston is in the hot seat after making a “retard” remark on Live! with Regis & Kelly.

Anniston was promoting her latest romantic comedy, “The Switch” on the said show. She was having a pleasant conversation with Regis Philbin and guest co-host Kristin Cruz from Los Angeles’ KOST 103.5 radio station when the r-word came rolling off the beauty’s tounge:

“Yes, I play dress up! I do it for a living, like a retard!”

Some of the audience find it funny but others did not. Some disability advocates found no joke about Jennifer’s “poor choice of words.”